Search on: FV FRAGMENT 
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Descriptor English:   Immunoglobulin Variable Region 
Descriptor Spanish:   Región Variable de Inmunoglobulina 
Descriptor Portuguese:   Região Variável de Imunoglobulina 
Synonyms English:   Antibody Fragment, Fv
Antibody Fragments, Fv
Fragment, Fv
Fragment, Fv Antibody
Fragment, Immunoglobulin Fv
Fragments, Fv
Fragments, Fv Antibody
Fragments, Immunoglobulin Fv
Framework Region, Ig
Framework Region, Immunoglobulin
Framework Regions, Ig
Framework Regions, Immunoglobulin
Fv Antibody Fragment
Fv Antibody Fragments
Fv Fragment
Fv Fragment, Immunoglobulin
Fv Fragments
Fv Fragments, Immunoglobulin
Ig Framework Region
Ig Framework Regions
Ig Variable Region
Ig Variable Regions
Immunoglobulin Framework Region
Immunoglobulin Framework Regions
Immunoglobulin Fv Fragment
Immunoglobulin Fv Fragments
Immunoglobulin V
Immunoglobulin Variable Regions
Regions, Immunoglobulin Variable
Variable Region, Ig
Variable Region, Immunoglobulin
Variable Regions, Ig
Variable Regions, Immunoglobulin  
Tree Number:   D12.644.541.500.650.500
D12.776.124.486.485.680.650.500
D12.776.124.486.485.797
D12.776.124.790.651.680.650.500
D12.776.124.790.651.797
D12.776.377.715.548.680.650.500
D12.776.377.715.548.797
G02.111.570.060.425
Definition English:   That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions. 
Pharmacological Action:   Immunologic Factors
 
See Related English:   Binding Sites, Antibody
Immunoglobulin Domains
 
History Note English:   84(77); was see under BINDING SITES, ANTIBODY 1977-83 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PD pharmacology
PH physiology PO poisoning
RE radiation effects TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   22209 
Unique Identifier:   D007135 

Occurrence in VHL: 		 

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